BDBM50396019 4'-(phenethylcarbamoyl)-[2,2'-bipyridine]-4-carboxylic acid (N3)::CHEMBL2169917

SMILES OC(=O)c1ccnc(c1)-c1cc(ccn1)C(=O)NCCc1ccccc1

InChI Key InChIKey=DSGOLESVOJUGOK-UHFFFAOYSA-N

Data  12 IC50  2 Kd

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50396019   

TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Emory University

LigandPNGBDBM50396019(4'-(phenethylcarbamoyl)-[2,2'-bipyridine]-...)
Affinity DataIC50:  120nMpH: 7.2 T: 2°CAssay Description:Reactions were performed in 50 mM HEPES [pH 7.2 for KDM5 or pH 7.5 for KDM4A(1-350)] containing 0.01% BSA and 0.01% Tween-20. To each well, 3 μL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Emory University

LigandPNGBDBM50396019(4'-(phenethylcarbamoyl)-[2,2'-bipyridine]-...)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibition of N-terminal his6-tagged human KDM5B (1 to 769 residues) expressed in sf9 insect cells incubated for 20 mins by Alphascreen assayMore data for this Ligand-Target Pair
In DepthDetails PubMed